Local and systemic assessment of LL-2 in children [9-14 years old] with severely inflamed gingiva

Measuring of interleukin-2 [IL-2] in gingival tissue and culture supernatants from children with gingival specimens were assayed for its presence. Ten gingival specimens from 10 patients and five blood supernatant samples assayed for presence of IL-1 IL-2 were significantly elevated in culture supernatants as well as tissue in comparison to normal [control] specimens. These results provided an evidence for the activation of immune cells in gingivitis, and suggested the role for IL-2 in the pathogenesis of the disease in children